Tuesday, November 13, 2012

New way to model human disease 'Lung-on-a-chip' sets stage for next wave of research


http://news.harvard.edu/gazette/story/2012/11/new-way-to-model-human-disease/?utm_source=facebook&utm_medium=social&utm_campaign=fb-wall



78 comments:

  1. What i found interesting about this is that it is crystal clear flexible polymer and that it is the size of a memory stick. That it is one side is lined with human lung cells from the air sac.

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  2. This article is about the lung on a chip. the vacuum recreates the way the lungs physically expands. One thing I found interesting about this article was that This has a major toxic side effect. It is a very deadly condition in which the lungs fill with fluid and blood clots.

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  3. One thing I found especially interesting about this Article is The fact That we have found a way to replicate basic human functions, such as breathing. Who knows where this could lead, As technology advances and humans gain more insight into the workings of the body. Maybe one day we'll be able to live hundreds of years, Just by the powers of science.

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  4. Although this lung chip can be effective in a good way, it also has a horrible side effect. This side affect includes high toxic waist that makes the lungs fill up with fluid and sometimes can cause blood clots.

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  5. The things I found interesting about this article is the fact that this lung on a chip Physically expands because of the vacuum recreates this function of the lungs. It is interesting to me that they were able to line one side of it with human lung cells from the air sac to recreate the functions of the lung.

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  6. The "lung-on-a-chip" is a good way for research on human organs. However a toxin called IL-2 which is a common side effect of the "lung-on-a-chip" can be fatal for the person using the product. Even though they can reduce this side-effect by reducing the amount of air being pushed into the lungs, it still doesn't seem like the best way to go in my opinion until they can erase all of IL-2 in the "lung-on-a-chip".

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  7. I'm very fascinated by the "Long-on-a-chip" research. It open up new gateways to the medical industry. It could very well make researching cells, species, and human blood much easier. A great idea.

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  8. I am extremely interested in the "Lung-on-a-chip" technological advances. The only thing I can see wrong with such advancement is the common side affect that the "Lung-on-a-chip" has. The side affect, being a toxin called IL-2, can be fatal to the person who may be using the chip. Overall without the side affect I think the medical field has advanced so far into medical studies. This seems like an okay technological advancement, might not be for the already ill but it could help out a lot.

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  9. I believe this is a good idea but, the side effects make it not such a good idea. I'm pretty sure noone wants fluid in their lungs just because of a chip. And, I'm pretty sure they definitely don't want blood clots.

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  10. The lung-on-a-chip is a really good thing for medical reasons and scientifically. I'm surprised that by this bionic-lung they've designed because it will now give us a more better insight into how our bodies work. Along with so it will also help to find out how the body reacts to things and can help find new treatments for disease and this all is very intreaging.

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  11. This can be very helpful in many ways, but it also has awful side affects. It causes your high toxic waist to build up in your lungs and can cause blood clots.

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  12. The lung-on-a-chip is very interesting to me. Although, I'm still debating whether or not it is going to help today's society. Hopefully all of this research won't go to waste.

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  13. i think that this is a good idea but the side effects might be a problem. it is very interesting.

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  14. This seems like it could be useful. It is also interesting to me. I don't know if it will help today's society or not. I just know that the side affects seem awful.

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  15. The "lung-on-a-chip" can be a great idea

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  16. that "lung-on-a-chip" looks very useful and it can use some research to make the side effects die down a bit.

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  17. If this idea takes off and all the kinks are worked out this idea has the potential to erase animal testing and can remove the harmful effects of human testing. By using these "Organs-on-a-chip" we can greatly reduce the time needed for testing before the production of new medicine.

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  18. I think that this can become very useful to people whom need lugs/lung cells.

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  19. The idea "Lung on a chip" caught my attention. This is interesting, but they side affects ain't worth the risk.

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  20. This seems to be a good idea. I think it's a great thing if it can help with studies about certain diseases. It could end animal testing.

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  21. The lung-on-a-chip is very interesting to me. Although, I'm still debating whether or not it is going to help today's society. Hopefully all of this research won't go to waste.

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  22. One thing that caught my eye was the toxin it mentioned. That probably doesn't make this the safest invention. So this invention is making me unsure weather or not this is going to help our society.

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  23. It can be toxic.It probably isn't safe.

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  24. I'm very fascinated by the "Long-on-a-chip" research.So this invention is making me unsure weather or not this is going to help our society.

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  25. This seems like it could be useful. It is also interesting to me. I don't know if it will help today's society or not. I just know that the side affects seem awful. Lung on a chip the name even sounds cool wow and its very interesting. but its toxic so it isn't safe so i don't like it to much but it is interesting. But will it help are society?

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  26. The things I found great about this article is the fact that this lung on a chip Physically expands because of the vacuum recreates this function of the lungs. It is interesting to me that they were able to line one side of it with human lung cells from the air sac to recreate the functions of the lung.

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  27. I think it could be something a lot of people would look at or do more research on and they would also see the side affects causes you could have like blood clots.

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  28. I think a lot of people would like this! It could be a good thing but then again it can be a bad thing.

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  29. It could probably be very useful.. But the side effects to it seem like they would be awful.

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  30. Its a way to diagnose disease so sounds helpful to me!

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  31. its a way to express the disease and that can come helpful

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  32. This article is very interesting in the fact that they have found a way to replicate a complex human disease in a microchip. This could help with major discoveries in medicine and could be very useful with coming up with new ways to treat various diseases.

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  33. I found the "organs-on-chips" design to be very fascinating. This is a major breakthrough in the science of medicine and the development of cures for complex diseases.

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  34. I think this would be very helpful because it makes it easier to examine human organs.

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  35. This can be very helpful in many ways, but it also has terrible side affects. It causes your high toxic waist to build up in your lungs and can cause blood clots.

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  36. It would actually help doctors. It would probably make their jobs a whole lot easier.

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  37. i think it would help doctors more and it would be easier for them to diagnose the disease.

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  38. This article is very interesting in the fact that they have found a way to replicate a complex human disease in a microchip.

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  39. Interesting how one might be able to replicate a human disease on to a tiny micro-chip.

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  40. This is a great invention to think that they actually have the technology to do all this is astounding

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  41. This is a very interesting article. It is amazing that doctors can study toxicity and could prevent life-threatening conditions because of the microchip. I would make things easier for doctors and take a whole lot of stress off them. If doctors have less stress, they would perform their jobs better.

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  42. This is very interesting to me that the blood flows up to the lungs when you breathe in fresh air.

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  43. I think it could help doctors diagnose diseases better. But it also has many bad side effectss, like blood clots in the air space.

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  44. This will help smokers who have bad lungs from smoking to help them breath. I would really like to see this invention be produced and help people.

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  45. I think his is a scientific break threw and could be used to saved life in the future.

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  46. i think that it would be an good thing for us because it would be easier for doctors.

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  47. i think it is very interesting how we are able to replicate the process of a human breathing. Its good because now we can do more extensive research without having to do animal or human testing. I really like how they could actually see why and how the lungs fill with liquids and form clots.

    luke lay

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  48. This seems to be a good idea. I think it's a great thing if it can help with studies about certain diseases. It could end animal testing. They have already used it to find out that doctors who treat patients on a respirator with IL-2 need to reduce the tidal volume of air that is being pushed into the lungs so that fluid leakage will not increase. This is great.

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  49. I think that this is probably a great idea. It can give scientists a better understanding of how certain drugs will effect humans, as it acts like actual functioning human organs, rather than testing on animals, which may or may not be completely accurate.

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  50. The chip was made to to help blood flow and air flow in a certain organ. Which makes it easier to model human diseases.

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  51. This sounds like a really good idea to me, I think it will be very helpful. I think it will help with the studies of different diseases. I really like this idea because it could end animal testing.

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  52. This idea is surprising but it could help people. It identifies a disease without the life threatening conditions. It could save you because of some toxics that could be inside you but with chip inside your lungs, they could see whats going on inside you.

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    Replies
    1. Since it isn't actually inside your body, scientists doesn't have to test on people or animals. They lay it on a table and it acts like your lung so doctor don't have to test on anything they can just look at you and see what's going on inside your body.

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  53. One thing I found interesting about this article is that the vacuum creates the way the lungs expands, and that long-on-a-chip is a helpful solution and it can use the research to help the side-effects go away in a short time period.

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  54. I think it's interesting that they can use the chip to see how different drugs affect people. The fact that they can put lung cells in the chip. It's amazing that they can use a chip to replicate the human body.

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  55. The microchip is very useful. This chip has very high potential to identify new therapies to prevent life threatening conditions. The chip would help a lot to stop testing on animals or in the future it would be able to stand in for animal testing.

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  56. I think this chip is really fasinating because its not actually in your body and it doesn't have to be in your body in order to function properly. It could really help doctors when trying to cure new diseases because they don't have to use test subjects, they can just work with the lung chip.

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  57. What I found interesting about this article is that it can identify life threatening conditions. The lung on a chip, the chip is like a flexible crystal clear polymer about the size of a memory stick. The chip is not inside your body. However it can help the doctor with studies about diseases without testing animals or other things. the reason this is important is because it is animal cruelty and you are not suppose to be doing test on animals without government consent.Lawsuits can be filed if this is happening. Hopefully it can speed up researches on diseases and other things.

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  58. I think that the chip would probably be very useful because you can do whatever you want to with it without messing with the human body. It's weird how you can use one little chip to figure out anything going on with your body without having to have surgery. It helps doctor's identify diseases better.

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  59. i think it is pretty cool that they would even think of somthing like that,also i think the side effects are a little risky.

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  60. i think it is a cool idea to experiment with but i think it is a little risky too.

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  61. The chip was made to to help blood flow and air flow in a certain organ.It's amazing that you can experiment on it and not a human body. The chip is not inside your body. But it can help the doctor with studies about diseases without testing animals or other things.

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  62. I think this could be a very helpful idea but the side effects are the down grade of this article. I think this could possibly work. Its a great idea that they can experiment on the chip instead of your body. They could hopefully save many lives and get things done a lot faster and easier.

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  63. They used this lung-on-a-chip to study drug toxicity and identify potential new therapies to prevent this life-threatening condition. It seems like a great idea, considering the chip is not in your body. Hopefully this study won't go away and they'll improve the side affects.

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  64. I think that using a chip is way cheaper than making a model or some other type of way of testing what can all happen to your lungs.I think they need to continue to do this and show young adults the result of doing certain things you don't need to do.

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  65. This article is very interesting to me. I found that this lung-on-a-chip can be very helpful in ways but very disturbing in other ways. It can help doctors by giving them information on diseases and it helps that they can stop animal testing. It has a down side because it can cause the lungs to fill with fluids and also cause blood clots.

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  66. The chip can be helpful. some might not like the idea of the chip but it helps doctors get more info on you and ect.

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  67. In some ways it is weird, but in other ways it is cool. One way it is neat is how they discovered the dose leakage and now know to use less IL-2. But it is strange because of the way that they actually made this sort of "bio-technical mini lung."

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  68. This article really had me confused. But To really think about it the "long-on-a-chip" may or may not be a good idea because some people think very different. I think the chip can be very helpful if not anything else.

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  69. This could be helpful to people. I don't think it would be bad at all.

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  70. I think this can help people in need and that need the help.But long-on-a-chip can but good because it help people and make life better.Then it can be bad because people can think negative and mess them up with the help problem.

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  71. I like the fact that our technology today has grown so much that we can help people with lung problem by putting a microchip in them. It just scares me the fact that they can get a terrible condition that fills their lungs with fluid and blood clots that kill them. It just goes back to a thing in a lot of medicines is the helpfulness of the lung-on-a-chip ,or any other medicine, worth the risk.

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  72. the idea Lung-on-a-chip was a great idea would be interesting to see happen

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  73. this is wonderful that the idea of a lung on a chip can help just by using technology but what will happen if the computer has a techical problem or a comuter genius hacks it and messes it up what would happen then would it put that person in serious danger or could they survive so is it really helpful or is like a gamble you do it and hope nothing goes wrong

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  74. I think the idea of a lung-on-a-chip is kind of fascinating and interesting! Making it a little more easier on doctors. It also opens up ways to help the medical industry.

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